Prediction of Geraniol Bond Mode in Aspergillus niger Linalool Dehydratase – Isomerase
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چکیده
منابع مشابه
Enantiospecifi c ( S ) - ( + ) - Linalool Formation from β - Myrcene by Linalool Dehydratase - Isomerase
In enzyme-catalyzed processes, the reaction pathway is defi ned by the enzyme and its complex with the substrate. The active site of an enzyme structure determines the interaction with the substrate which often results in high stereospecifi city. Classical examples are the reduction of nicotinamide-adenine-dinucleotides (NAD and NADP) and of aldehydes, the hydration of fumarate, and aldose-keto...
متن کاملCharacterization of a foldase, protein disulfide isomerase A, in the protein secretory pathway of Aspergillus niger.
Protein disulfide isomerase (PDI) is important in assisting the folding and maturation of secretory proteins in eukaryotes. A gene, pdiA, encoding PDIA was previously isolated from Aspergillus niger, and we report its functional characterization here. Functional analysis of PDIA showed that it catalyzes the refolding of denatured and reduced RNase A. pdiA also complemented PDI function in a Sac...
متن کاملStructural and functional insights into asymmetric enzymatic dehydration of alkenols.
The asymmetric dehydration of alcohols is an important process for the direct synthesis of alkenes. We report the structure and substrate specificity of the bifunctional linalool dehydratase isomerase (LinD) from the bacterium Castellaniella defragrans that catalyzes in nature the hydration of β-myrcene to linalool and the subsequent isomerization to geraniol. Enzymatic kinetic resolutions of t...
متن کاملGlycosidases of Aspergillus niger
A highly purified preparation of 1,2-oc-L-fucosidase, free of /3-galactosidase and P-N-acetylglucosaminidase activities, has been obtained from a commercial preparation of Aspergillus niger by a simple isolation procedure involving ammonium sulfate precipitation, pressure dialysis, repeated gel Cltration on Sephadex G-150, and chromatography on diethylaminoethyl Sephadex A-50. The enzyme has a ...
متن کاملLysine aminopeptidase of Aspergillus niger.
Conserved regions within the M1 family of metallo-aminopeptidases have been used to clone a zinc aminopeptidase from the industrially used fungus Aspergillus niger. The derived amino acid sequence of ApsA is highly similar to two yeast zinc aminopeptidases, LAPI and AAPI (53.3 and 50.9% overall similarity, respectively), two members of the M1 family of metallo-aminopeptidases. The encoding gene...
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ژورنال
عنوان ژورنال: Majalah Obat Tradisional
سال: 2019
ISSN: 2406-9086,1410-5918
DOI: 10.22146/mot.45599